GEP breast

Gene Expression Profiling (GEP) in breast cancer

 

A convention was concluded between the RIZIV/INAMI and recognised breast clinics for the reimbursement of 'Gene Expression Profiling (GEP)' tests for a specific group of patients with early breast cancer. These GEP tests determine the genetic profile of the tumour to assess the susceptibility to adjuvant chemotherapy whereby unnecessary chemotherapy can be avoided. More information about this convention can be found on the website of the RIZIV/INAMI.

 

The convention defines the target group as followed:

-         Patients with early breast cancer, first diagnosis, with maximum 3 affected lymph nodes, a tumour of maximum 5 cm, HER2-, ER+ and/or PR+, after primary surgery without prior neoadjuvant systemic therapy.

 

This convention is linked to a compulsory registration of all patients from the target group via the Belgian Cancer Registry, independent of GEP request. Reimbursement of the GEP test is linked to this registration. 

This registration consists of two datasets:

1.      The general (MOC) cancer registration (Bijlage/Annexe 55)

2.      The project-specific GEP Breast registration (dataset)

 

The starting date of the convention is 1/07/2019 (i.e. date of MOC/COM discussion where it was decided whether or not to request a GEP test). Complete registrations (both datasets) for all patients within the target group should be delivered yearly by the last day of February for the cases with a MOC/COM discussion in the previous year.

 

Registrations can be delivered to the Belgian Cancer Registry in two ways:

-         Via the Web Based Cancer Registration (WBCR) application of the Cancer Registry (project module 'GEP Breast'). More information about the use of this online application is available in the WBCR manual.

                          

                                     

-         In batch via a predefined format. This format and the desired sequence of variables is available in 'the batch file template' .

 

Expected in November/December 2019:

-         Registration manual

-         Online registration training

 

If you would like more information about the 'GEP breast' registration project, you can contact us via GEPbreast@kankerregister.org or on 02/250 10 10.